What Do Dermatologists Say About Niacinamide? The Clinical Verdict | Rysun Biotech

Monday, 12/15/2025

Curious what do dermatologists say about niacinamide? Experts call it the "universal" ingredient. Learn how Rysun Biotech’s R&D aligns with medical standards to manufacture safe, high-efficacy serums.

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What Do Dermatologists Say About Niacinamide? A Manufacturer’s Perspective on the Clinical Verdict

Introduction
In the world of skincare, trends are often driven by social media. However, there are few ingredients that bridge the gap between viral trends and actual medical advice. Niacinamide (Vitamin B3) is one of them. But for brand owners looking to formulate a credible product, the most important question is: "What do dermatologists say about niacinamide?"

At Guangzhou Rysun Biotechnology, our company ethos is built on listening to experts. Established in 2014 by Ivy Wong after recognizing inconsistent market quality through discussions with a Swiss anti-aging expert, we have always prioritized science over hype. With a Research Institute backed by 20 leading scientists and professors, we align our manufacturing standards with dermatological consensus.

Here is the breakdown of what the medical community says about this powerhouse ingredient and how Rysun translates that into product excellence.

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1. The Verdict: It is the "Universal" Ingredient

Dermatologists often refer to Niacinamide as the "Swiss Army Knife" of dermatology.

  • What they say: Unlike Retinol (which can burn) or Vitamin C (which can be unstable), Niacinamide is generally tolerated by every skin type, including those with Rosacea, Eczema, and Acne.
  • How Rysun Applies This: We leverage our 105 product patterns to create versatile formulations. Whether a brand is targeting teenagers with acne or mature skin with dryness, our R&D team uses Niacinamide as the safe, stabilizing backbone of the formula.

2. The Verdict: Concentration Matters (Less is More)

This is the most common critique dermatologists have of the current market.

  • What they say: Many doctors warn against the trend of 15% or 20% Niacinamide serums. Clinical studies show that the "therapeutic window" (where it works best with least irritation) is actually 2% to 5%. Higher percentages increase the risk of irritation without necessarily increasing benefits.
  • How Rysun Applies This: We believe in practical solutions. While we can manufacture high concentrations if requested, our scientists advise our 700+ brand partners to stick to the dermatologically supported 5% "Golden Ratio." This ensures high efficacy and low returns due to irritation.

3. The Verdict: It is Essential for Barrier Repair

Dermatologists agree that a healthy lipid barrier is the foundation of good skin.

  • What they say: Niacinamide triggers the skin to produce its own Ceramides. Doctors often recommend it to patients who have damaged their skin barrier through over-exfoliation.
  • How Rysun Applies This: We formulate for restoration. Our serums often pair Niacinamide with Hyaluronic Acid or Panthenol to create a "barrier rescue" system, a highly sought-after category in the 50+ countries we export to.

4. The Verdict: Purity is Non-Negotiable

Dermatologists often see patients with contact dermatitis caused by "cheap" Niacinamide products.

  • What they say: Low-quality Niacinamide can be contaminated with Nicotinic Acid, which causes vasodilation (flushing/redness) and burning.
  • How Rysun Applies This: This brings us back to our founder’s mission to eliminate inconsistent quality. We implement up to 50 inspection procedures per product. We test for residual Nicotinic Acid to ensure our Niacinamide is pharmaceutical grade—the kind a dermatologist would feel safe recommending.

 

Why the "Research-Driven" Approach Wins

When a consumer asks, "What do dermatologists say about niacinamide?", they are looking for trust. They want to know the product is safe.

Rysun Biotechnology operates with the precision of a laboratory and the capacity of a global manufacturer.

  • 253 Intellectual Properties: We don't just mix ingredients; we own the technology that stabilizes them.

  • Multidisciplinary Team: Our team includes doctors and professors in dermatology and pharmacology. We don't just read what dermatologists say; we have them on our team.

Conclusion

So, what do dermatologists say about niacinamide? They say it is essential, provided it is formulated correctly (right pH, right percentage, high purity).

At Rysun Biotechnology, we take this medical advice and turn it into manufacturing reality. Partner with us to create a Niacinamide serum that meets the rigorous standards of the medical community and the high expectations of your customers.

 

FAQs

Q1: Do dermatologists recommend Niacinamide for acne?
A: Yes. It is considered a first-line cosmetic treatment because it reduces oil production and calms the inflammation (redness) associated with breakouts, without the dryness caused by Benzoyl Peroxide.

Q2: Is 10% Niacinamide safe according to doctors?
A: Most dermatologists consider 10% safe for oily skin types, but warn it may be too strong for sensitive skin. Rysun recommends 5% for general market products to ensure broad tolerance.

Q3: Can Niacinamide cause "purging"?
A: Unlike Retinol or Acids, Niacinamide does not increase cell turnover, so it should not cause purging. If a user breaks out, it is likely due to the base formula (pore-clogging oils) or irritation. Rysun formulations are tested to be non-comedogenic.

Q4: Do dermatologists support mixing Niacinamide and Retinol?
A: Yes! In fact, many recommend using Niacinamide before Retinol. The Niacinamide strengthens the barrier, helping the skin tolerate the Retinol better. Rysun specializes in manufacturing these compatible systems.

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