How to Use Retinol Serum: A 5-Step Expert Guide for Beginners | Rysun Biotech

Friday, 12/19/2025

Unsure how to use retinol serum? Avoid irritation with our expert guide. Rysun Biotech’s R&D team explains the "Low and Slow" method backed by Swiss-inspired anti-aging science.

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Mastering the Youth Molecule: How to Use Retinol Serum Correctly

Introduction
Retinol is widely regarded as the "Holy Grail" of anti-aging. However, it is also the ingredient most likely to be returned by unhappy customers due to irritation. The problem is rarely the ingredient itself; it is the user not knowing how to use retinol serum correctly.

At Guangzhou Rysun Biotechnology, we believe education is as important as formulation. Founded in 2014 by Ivy Wong to solve the industry's issue of "inconsistent quality," and inspired by insights from a Swiss anti-aging expert, we approach Retinol with medical-grade precision.

Backed by our Research Institute and 20 leading scientists, here is the definitive guide on incorporating this potent active into a routine safely and effectively.

Here is our private label face serum collection, pls click here for more details.

 

Step 1: The "Dry Skin" Rule (Crucial)

Most serums (like Hyaluronic Acid) love damp skin. Retinol does not.

  • The Science: Water increases the permeability of the skin. If you apply Retinol to damp skin, it absorbs too quickly, which can trigger stinging and redness.
  • The Rysun Method: After cleansing, wait 5 to 10 minutes until your skin is completely dry before applying your Retinol serum.

Step 2: The "Pea-Sized" Amount

When learning how to use retinol serum, less is more.

  • The Science: Retinol is potent. Applying a thick layer won't make it work faster; it will only damage your moisture barrier.
  • The Rysun Method: Dispense a pea-sized amount for the entire face. Dot it on the forehead, cheeks, and chin, then smooth it out.
  • R&D Insight: Rysun’s 105 product patterns include high-spreadability textures, ensuring that a small amount covers the whole face evenly without dragging.

Step 3: The "Sandwich Method" (For Sensitive Skin)

If you are new to Retinol, our experts recommend buffering the intensity.

  • The Method:

    • Apply a layer of lightweight moisturizer.

    • Apply your Retinol serum.

    • Apply a second layer of moisturizer.

  • Why it works: This creates a buffer that slows down absorption without stopping the Retinol from working. It aligns with Rysun’s core value of providing "Practical Solutions" that make professional skincare accessible to everyone.

Step 4: Frequency – The "Low and Slow" Approach

Do not start using it every night.

  • Week 1-2: Apply once every 3 nights.
  • Week 3-4: Apply every other night.
  • Week 5+: If your skin tolerates it, move to nightly use.
  • R&D Insight: Our stability testing shows that consistent, long-term use yields better anti-aging results than sporadic, aggressive application.

Step 5: The Morning After – SPF is Mandatory

You cannot learn how to use retinol serum without learning about sun protection.

  • The Science: Retinol reveals fresh, new skin cells that are vulnerable to UV damage.
  • The Rule: You must wear SPF 30 or higher the next morning. If you skip this, you negate the anti-aging benefits.

 

The Rysun Advantage: Why Formulation Matters

Even if a consumer follows these steps perfectly, a bad product will still cause issues. Unstable Retinol degrades into irritants.

Rysun Biotechnology ensures safety through science:

  • Encapsulation: We use 253 intellectual properties to encapsulate our Retinol. This protective shell allows the ingredient to release slowly into the skin over several hours, significantly reducing the "bite" or sting associated with generic Retinols.
  • Purity: We implement up to 50 inspection procedures to ensure our serums are free from impurities that exacerbate irritation.

Conclusion

Knowing how to use retinol serum is the key to unlocking youthful skin without the side effects. It requires patience, dry skin application, and sun protection.

However, the best routine starts with the best product. At Rysun Biotechnology, we combine over 10 years of manufacturing excellence with Swiss-inspired R&D to create Retinol serums that are stable, effective, and gentle enough for new users. Partner with us to manufacture a Retinol product that your customers will love, not return.

 

FAQs

Q1: Can I put Retinol under my eyes?
A: Yes, but be careful. The skin there is thin. Rysun recommends mixing a tiny drop of Retinol serum with your eye cream, or using a specific "Eye Retinol" formula we manufacture that is adjusted for that delicate area.

Q2: What happens if I use too much Retinol?
A: You will likely experience "Retinoid Dermatitis"—redness, peeling, and burning. If this happens, stop using it for a few days and focus on barrier repair (Ceramides/Hyaluronic Acid) until the skin heals.

Q3: Can I use Retinol with Vitamin C?
A: Do not use them at the same time. Use Vitamin C in the morning and Retinol at night. This prevents irritation and ensures both ingredients remain stable.

Q4: Is tingling normal when applying Retinol?
A: A slight tingle is normal for beginners. However, intense burning is not. If it burns, wash it off immediately. You may need a lower concentration or a "Slow-Release" formula like those manufactured by Rysun.

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