Who Should Avoid Hyaluronic Acid Serum? Safety & Formulation Guide | Rysun Biotech

Wondering who should avoid hyaluronic acid serum? The answer is rare, but specific skin conditions or climates require caution. Learn how Rysun Biotech’s R&D ensures safety for all skin types.

Who Should Avoid Hyaluronic Acid Serum? A Scientific Guide to Safety and Suitability

Introduction
Hyaluronic Acid (HA) is often called the "universal" skincare ingredient. Because it naturally occurs in the human body (in joints, eyes, and skin), it is biocompatible and generally safe. However, with the explosion of skincare products on the market, consumers and brand owners are asking a critical question: "Who should avoid hyaluronic acid serum?"

At Guangzhou Rysun Biotechnology, we believe that safety comes first. Founded in 2014 by Ivy Wong to combat the industry's "inconsistent quality," and guided by insights from a Swiss anti-aging expert, we approach this question with clinical precision.

While true "avoidance" is rare, there are specific scenarios where HA can do more harm than good if the formulation is poor. Here is our expert guide on who needs to be careful.

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1. Those with a History of Avian (Bird) Allergies

This is a rare but historical concern.

• The Risk: In the past, Hyaluronic Acid was often extracted from rooster combs (animal tissue). People with severe egg or bird protein allergies had to avoid these products.
• The Rysun Solution: Today, this is largely a non-issue if you choose the right manufacturer. Rysun uses strictly bio-fermented Hyaluronic Acid (derived from bacteria or wheat). Our serums are 100% vegan and safe for those with animal protein allergies.

2. People Living in Extremely Dry Climates (Without a Seal)

If you live in a desert or an area with near-zero humidity, you might want to avoid pure HA serums that lack occlusives.

• The Risk: HA is a humectant. It pulls water from the nearest source. If the air is dry, it will pull water out of your skin to the surface, where it evaporates. This leaves the skin tighter and more dehydrated.
• The Rysun Solution: We formulate Practical Solutions. For brands selling in dry regions (among the 50+ countries we export to), we add locking agents like Polyglutamic Acid or Ceramides. This creates a barrier, allowing even "desert dwellers" to use HA safely.

3. Those with Severe Rosacea (Sensitive to Inflammation)

While HA is soothing, molecular weight matters.

• The Risk: Some studies suggest that extremely low molecular weight HA (Nano-HA) can penetrate too quickly and trigger an inflammatory response in hyper-sensitive skin conditions like Rosacea.
• The Rysun Solution: Precision R&D. Backed by 253 intellectual properties, Rysun’s researchers balance the molecular weight. We avoid pro-inflammatory fragments and use soothing, medium-weight molecules that hydrate the surface without aggravating the skin's immune system.

4. People with Compromised Skin Barriers (Using Acidic Formulas)

If your skin is raw, cracked, or bleeding (perhaps from over-exfoliation), almost anything will sting.

• The Risk: Low-quality HA serums often use cheap preservatives or have a pH that is too acidic, causing "sting shock" on compromised skin.
• The Rysun Solution: Strict Quality Control. We implement up to 50 inspection procedures per product. We carefully adjust the pH of our sensitive skin serums to be bio-compatible (around 5.5), reducing the "sting" factor significantly.

The Verdict: Almost No One Needs to Avoid It

The truth is, who should avoid hyaluronic acid serum? Almost no one—provided the serum is high quality.

Most negative reactions come from:

• Impurities in the raw material.

• Improper usage (applying to dry skin).

• Unbalanced formulations (too much alcohol or fragrance).

Rysun Biotechnology was built to eliminate these variables. With our Research Institute established in 2015 and a team of 20 leading scientists, we ensure that our HA formulations are clean, stable, and safe for virtually every demographic.

Conclusion

Hyaluronic Acid remains the gold standard for hydration. The question isn't "Should I avoid it?", but rather "Is my manufacturer making it correctly?"

At Rysun Biotechnology, we combine Swiss-inspired standards with advanced manufacturing to create HA serums that are safe, effective, and inclusive. Partner with us to deliver hydration that everyone can trust.

FAQs

Q1: Can I use Hyaluronic Acid if I have fungal acne?
A: Generally, yes. Hyaluronic Acid itself is safe for fungal acne. However, you must avoid serums containing esters, fatty acids, or oils that "feed" the yeast. Rysun’s microbiology team can formulate specific "fungal-acne safe" HA serums that are oil-free.

Q2: Is Hyaluronic Acid safe during pregnancy?
A: Yes, it is widely considered safe for use during pregnancy and breastfeeding. Rysun ensures our formulas are free from retinoids or harmful additives, making them a worry-free choice for expecting mothers.

Q3: Why does my skin turn red after using HA?
A: This is likely not an allergy to HA, but a reaction to a preservative (like Phenoxyethanol) or a penetration enhancer (like Propylene Glycol) in the formula. Rysun specializes in minimalist formulations for sensitive skin to avoid this.

Q4: Can I use Hyaluronic Acid while undergoing chemotherapy?
A: Chemotherapy often causes extreme skin dryness. While you should always consult a doctor, HA is generally recommended for relief. Rysun’s gentle, fragrance-free formulations are ideal for oncology aesthetics due to their purity and soothing properties.