Which Acid Is Best to Remove Dark Spots? A Scientific Comparison Guide | Rysun Biotech

Monday, 01/12/2026

Asking "Which acid is best to remove dark spots?" We compare Glycolic, Kojic, Tranexamic, and Vitamin C. Discover how Rysun Biotech’s Swiss-inspired R&D formulates the ultimate brightening solutions.

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Which Acid Is Best to Remove Dark Spots? A Scientific Comparison for Radiant Skin

Introduction
Hyperpigmentation—whether from sun damage, acne scars, or hormonal changes—is one of the most stubborn skin concerns globally. While the market is flooded with "brightening" claims, the real power lies in acids. But with so many options, brand owners and consumers alike are left asking: "Which acid is best to remove dark spots?"

At Guangzhou Rysun Biotechnology, we answer this question with biological precision. Founded in 2014 by Ivy Wong to solve the industry's "inconsistent quality," and inspired by deep discussions with a Swiss anti-aging expert, we know that not all dark spots are the same—and neither are the acids that treat them.

Backed by our Research Institute and 20 leading scientists, we are here to compare the top contenders. We will break down which acid works best for which type of spot, and how Rysun’s superior manufacturing ensures these potent ingredients remain safe and stable.

 

The Comparison: Exfoliators vs. Inhibitors

To choose the "best" acid, you must understand how they work.

  • Exfoliators (AHAs/BHAs): They peel away the surface skin where the dark pigment is trapped.
  • Inhibitors: They stop the enzyme (tyrosinase) from creating new pigment deep in the skin.

Here is the breakdown of the top 4 acids we manufacture for our 700+ brand partners:

1. Glycolic Acid (The Surface Polisher)

  • Type: Alpha Hydroxy Acid (AHA).
  • Best For: Sun spots and overall dullness.
  • How it Works: It has the smallest molecular size of all AHAs, allowing it to penetrate quickly and dissolve the "glue" holding dead, pigmented cells together. It reveals fresh skin fast.
  • The Rysun Standard: We formulate Glycolic serums with precise pH buffering (pH 3.5–4.0). This ensures maximum exfoliation without the chemical burns associated with poorly made products.

2. Salicylic Acid (The Acne Fighter)

  • Type: Beta Hydroxy Acid (BHA).
  • Best For: Post-Acne Marks (PIH) and active breakouts.
  • How it Works: It is oil-soluble. It dives into the pore to clear the blockage while exfoliating the dark mark left on the surface.
  • The Rysun Standard: We use advanced solubilizers to keep BHA stable without high alcohol content, preventing the dryness that often makes dark spots look worse.

3. Kojic Acid (The Pigment Blocker)

  • Type: Tyrosinase Inhibitor.
  • Best For: Melasma and stubborn age spots.
  • How it Works: It doesn't peel the skin; it turns off the pigment factory. It binds to copper to disable the enzyme responsible for melanin production.
  • The Rysun Standard: Kojic Acid is unstable (turns brown). Using our 253 intellectual properties, we utilize proprietary stabilization technology to keep our Kojic serums clear, potent, and effective for the long haul.

4. Tranexamic Acid (The Redness Reducer)

  • Type: Anti-inflammatory / Inhibitor.
  • Best For: Hormonal Melasma and Red Acne Scars (PIE).
  • How it Works: It prevents the interaction between skin cells and pigment cells. It is one of the few acids that addresses the vascular (redness) component of dark spots.
  • The Rysun Standard: This is a rising star in our export markets. We formulate it with soothing agents to create a gentle, barrier-safe brightening solution.

 

The Verdict: Which Acid is Best?

There is no single winner. The "best" acid depends on the root cause.

Spot Type The Winner Why?
Sun Spots (Surface) Glycolic Acid Peels away the damage quickly.
Acne Marks (Oily Skin) Salicylic Acid Treats the pore and the spot.
Melasma (Hormonal) Tranexamic Acid Targets the inflammatory trigger safely.
Stubborn Pigment Kojic Acid Stops pigment production at the source.
Overall Glow Vitamin C Brightens and protects (Antioxidant).

The Rysun Innovation: Why Choose One?

The smartest answer to "Which acid is best?" is: Synergy.
Modern R&D allows us to combine these acids safely.

  • The "Power Blend": We often manufacture serums containing Glycolic Acid (to peel) + Kojic Acid (to inhibit). This attacks the dark spot from above and below simultaneously.
  • Manufacturing Challenge: Mixing acids requires rigorous stability testing to ensure the pH doesn't drop too low over time.
  • The Rysun Solution: Our 50 inspection procedures ensure that our multi-acid blends remain stable and safe for consumer use, preventing irritation while maximizing results.

 

Conclusion

Which acid is best to remove dark spots?

  • Glycolic for peeling.
  • Kojic for inhibiting.
  • Tranexamic for hormonal calming.

At Rysun Biotechnology, we don't just pick ingredients; we engineer solutions. Whether you need a single-acid toner or a complex multi-acid serum, we have the Swiss-inspired expertise to manufacture it. Partner with us to create a dark spot corrector that delivers visible, safe, and stable results.

 

FAQs

Q1: Can I use all these acids together?
A: No, that is a recipe for chemical burns. Rysun recommends "Skin Cycling" or using a professionally formulated blend where the concentrations are balanced for safety.

Q2: Which acid works the fastest?
A: Glycolic Acid usually shows the fastest visible results (skin smoothness and brightness) within 1-2 weeks because it works on the surface. Inhibitors like Kojic Acid take 8-12 weeks to fade deep pigment.

Q3: Can I use these acids in the summer?
A: Yes, but SPF 50 is mandatory. Acids (especially AHAs) remove the protective dead skin layer, making you more susceptible to sun damage. Rysun advises marketing these as "Night Treatments."

Q4: Does Rysun make a serum for sensitive skin with dark spots?
A: Yes. For sensitive skin, we recommend Lactic Acid (a gentler AHA) or Tranexamic Acid (non-exfoliating). We formulate these with barrier-repairing ingredients to brighten without stinging.

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